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Stephen Barnes, PhD



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Dr. Barnes, Director of the Metabolomics Workshop, is Abettor of Pharmacology and Toxicology and has accessory accessories in bristles added departments.  He started his assay career in the class of A. T. (Tony) James, co-inventor of gas-liquid chromatography, belief blubbery metabolism in blooming algae and did his PhD on the carbohydrate metabolism of the acellular fungus cast Physarum polycephalum at Imperial College, University of London beneath the administration of Sir Ernst Boris Chain, 1945 Nobel Laureate for the assay of penicillin. He began his abiding absorption in acerbity acerbic metabolism at the Royal Chargeless Hospital with Dame Sheila Sherlock and Barbara Billing. After the winter of 1975 in Alan Hofmann’s lab at the Mayo Clinic in Rochester, he took up an action to appear to the University of Alabama at Birmingham (UAB) in 1977 area he has remained anytime since. In the aboriginal 1980s he activated aerial acreage NMR appliance superconducting magnets to break the proton NMR spectrum of acerbity acids as able-bodied as to use beating sequences to abundantly abridge the process. In 1992 he took over the development of LC-mass spectrometry in biomedical assay at UAB and was the Director of the UAB Comprehensive Blight Center Accumulation Spectrometry Shared Facility from 1992 to 2009. In 2009 he was appointed as the Director of the Targeted Metabolomics and Proteomics Class (TMPL).  He additionally was the Accessory Director of the Purdue-UAB Botanicals Center for Age-related Ache from 2000-2011 and the Director of the UAB Center for Nutrient-Gene Interaction from 2002-2010. These closing roles provided analytic acquaintance in beginning design, statistical assay of –Omics abstracts and the important role of the diet in chargeless the aftereffect of beginning models of abiding diseases.

More capacity about TMPL can be acquired at http://tmpl.uab.edu



Erin Baker, PhD



Dr. Erin Baker is a bioanalytical chemist with added than 16 years’ acquaintance utilizing ion advancement spectrometry in affiliation with accumulation spectrometry (IMS-MS) to abstraction ecology and biological systems. In the aftermost 10 years, she has formed primarily on IMS-MS applications in the acreage of proteomics and added afresh she has formed to optimize IMS-MS metabolomic, glycomic and lipidomic separations. Her assay involves the development and appraisal of high-throughput IMS-MS, SPE-IMS-MS and LC-IMS-MS analyses to bound abstraction abundant samples in a abbreviate time aeon after accident admired biological information, as able-bodied as assessing the cardinal and affection of appearance detected with IMS-MS for allegory with absolute MS platforms. Dr. Baker is additionally anon alive with the PNNL Informatics aggregation to architecture and apparatus software accoutrement that automatically assay the circuitous multidimensional SPE-IMS-MS and LC-IMS-MS data.

PNNL Website

Chris Beecher

IROA Technologies

Professor Chris Beecher is the Accessory Director of the South-East Center for Chip Metabolomics (SECIM) at the University of Florida, one of six NIH-funded Metabolomics Centers in the United States, and the Chief Science Officer for IROA Technologies (IROA).  The IROA protocols are a amount technology aural SECIM.  Abettor Beecher had ahead accustomed the aloof Metabolomics platforms at the University of Michigan (2007) in Ann Arbor, Michigan, and, above-mentioned to that, had developed the metabolomics platforms for Metabolon, a metabolomics-based aggregation (2004), and Paradigm Assay (1999) both in RTP, North Carolina.

Since 1999 Abettor Beecher’s assay focus has been on the connected development of the science of Metabolomics.  As the newest of the “Omics” sciences, establishing methods for college sensitivity, resolution and reproducibility, and algorithms for abstracts handling, and abstracts bearing are areas of advancing exploration.  The Lab actively collaborates with assorted advisers to accretion beginning systems that account from a metabolomic analytic approach, and accommodate new avenues for metabolomic exploration.

The Beecher metabolomic belvedere is 1) a MS-based analytic basal that is 2) able-bodied chip into a 3) absolutely automatic sample basal operation.  Affiliation requires that sample breeze is directed by a LIMS system, and an automatic informatics arrangement for processing advice generated aural the platform.  Due to the aerial akin of affiliation and automation one can put in abode a adamant affairs for absurdity abridgement and improvement.

Dr. Beecher holds a B.A. in Anthropology (New York University), M.S. Assay (New York University), and a Ph.D. in Pharmaceutical Sciences / Accustomed accessories Allure (University of Connecticut).  He began his assay into the high-throughput actinic assuming of circuitous mixtures while on the adroitness of the University of Illinois, College of Pharmacy (1985) area he captivated the position of Accessory Professor.  He was the editor of the NAPRALERT database from 1990 to 1998, Editor-in-Chief of the All-embracing Journal of Pharmacognosy, and served as a founding affiliate of the Functional Foods Affairs of the University of Illinois.

In 1997 he was arrive to abide this assay in the laboratories of Bristol-Myers Squibb, and Ancile Pharmaceuticals.  His focus confused from accessory metabolism to primary metabolism with the enactment of the aboriginal Metabolomics belvedere in America at Paradigm Assay from 1999 to 2002, and in 2003 founded of two Metabolomics-based companies; Metabolon, Inc. (focused on animal healthcare.) and Metabolic Analyses, Inc. (focused on the informatics issues associated with Metabolomics.)  Dr. Beecher aggregate the aboriginal animal metabolome in 2002 at Metabolic Analyses, and has been alive against the affiliation of metabolomic, proteomic, transcriptomic and genomic data.

Website

Ivana Blazenovic, PhD

Dr. Ivana Blazenovic is currently a column doctoral academic in the Fiehn lab at UC Davis alive on assorted pilot projects with focus on

• assay comment of baby molecules• LC-MS and IM-QTOF abstracts assay and interpretation• statistical abstracts analysis• adjustment development and validation

She has acquired her phD at TU Braunschweig, Germany in the acreage of Metabolomics and Microbiology and her MSc at University of Zagreb, Croatia in the acreage of Biotechnology.

Metabolomics Fiehn Lab

Pam Bounelis, PhD

Pam Bounelis, PhD, serves as the Assay Integrity Officer (RIO) and Abettor Vice President for Assay at the University of Alabama at Birmingham (UAB). She is additionally the Abettor Dean for Biomedical Assay in the UAB School of Anesthetic and accessory abettor in the Department of Cell, Developmental, and Commutual Biology. She accustomed her PhD in assay from the University of Illinois in Chicago (1985) and was recruited to UAB anon thereafter. In her role as RIO, Dr. Bounelis has albatross for the assay delinquency process. She has added than 15 years of acquaintance in amplitude programming and planning. She has been the advance or substantially‐contributing columnist on abounding alfresco proposals that accept resulted in about $90 actor of alfresco abutment to UAB for basal projects and accessories acquisition. She has served on four NIH appropriate accent panel/scientific assay groups. She is an alive affiliate of the American Affiliation of Medical Colleges Accumulation on Institutional Planning and is currently account as the Civic Chair.

Xiangqin Cui, PhD

I was initially accomplished as a lab/field geneticist and after on confused into statistical assay through my postdoctoral training. After abutting the UAB Department of Biostatistics, I accept been administering assay in genome-wide studies, such as gene announcement (both arrays and next-generation sequencing), abutting bearing sequencing, DNA methylation, metabolomics, and microbiome with added than 50 publications in these areas. I accept served as a Co-investigator/Biostatistician for statistical abstracts analyses in assorted adjourned grants involving omics studies. RNAseq assay specifically, I accept appear several affidavit listed beneath and accomplished this affair in civic abbreviate courses abounding times. The accepted appliance is adapted to my accomplishments and I am agog to help.

Website: http://www.soph.uab.edu/ssg/people/cui

Xavi Domingo, PhD

Dr. Domingo-Almenara acquired his PhD in Bioengineering at the University Rovira i Virgili (Catalonia, Spain), area he researched on automatic methods for the processing of accumulation spectrometry untargeted metabolomics data. As a bioinformatician, he has developed adapted chargeless and accessible antecedent computational accoutrement for processing of GC and LC-MS data, including the R amalgamation eRah. In 2017 he confused into the Scripps Assay Center for Metabolomics in La Jolla, California, area he serves as a postdoctoral adolescent with Prof. Gary Siuzdak. His assay focuses on evolving appear avant-garde computational workflows to accumulate targeted and untargeted assay in metabolomics, systems assay and -omic integration.

Xiuxia Du, PhD

Dr. Du is an Accessory Abettor of Bioinformatics at the Department of Bioinformatics and Genomics, University of North Carolina at Charlotte. She accustomed her Ph.D. in Systems Science and Mathematics from Washington University in St. Louis. Subsequently, she did a postdoc at the Pacific Northwest Civic Laboratory. She abutting the University of North Carolina at Charlotte in 2008 as an abettor professor. The assay of her accumulation has been absorption on the development of computational algorithms for accumulation spectrometry-based proteomics and metabolomics research.

Web Site: http://www.du-lab.org

Whei-Mei Teresa Fan, PhD

Dr. Teresa Fan, Abettor of Toxicology and adroitness affiliate of the Markey Blight Center and Center for Ecology Systems Biochemistry at the University of Kentucky, is one of the leaders of the Resource Center for Abiding Isotope-Resolved Metabolomics. Dr. Fan uses metabolomics to abstraction corpuscle metabolism in lung cancer. Appliance appropriate atomic accoutrement alleged abiding isotope tracers, she can characterization assertive types of metabolites and watch as they move through the complicated and commutual arrangement of biological reactions that accord to corpuscle metabolism. This affectionate of address is like “tracing breadcrumbs in the forest,” says Dr. Fan. She traces her metabolite “breadcrumbs” through a “forest” of blight beef developed in the laboratory, tumors in animals, and in animal patients with lung cancer. Dr. Fan and her assay aggregation systematically delving the metabolic arrangement of blight in these systems to analyze new corpuscle processes that could be targeted with drugs and ascertain analytic markers for early-stage lung cancer. With a assay admission from the NIH Common Fund Metabolomics program, Dr. Fan and her colleagues are developing means to amusement samples afore allegory them to access acuteness and stability. They are authoritative actinic agents that can adapt accurate genitalia of assertive metabolites, authoritative them easier to detect. This access could additionally enhance a researcher’s adeptness to analyze ahead alien metabolites.

Janusz Kabarowski, PhD

Janusz Kabarowski, PhD, Accessory Abettor of Microbiology. Dr. Kabarowski acquired his PhD in the acreage of hematopoiesis and leukemia at University College, London and did his postdoctoral training in immunology with Dr. Owen Witte at UCLA. His adeptness is in the abstraction of lipids in deepening and immunity. He has activated this adeptness to studies of lipid advised mechanisms authoritative deepening and autoimmunity appliance abrasion models of atherosclerosis, Lupus and tissue/organ injury. He is currently investigating approaches by which abeyant anti-inflammatory and immunosuppressive backdrop of HDL (linked to its adeptness to adapt cholesterol homeostasis and abolish pro-inflammatory and breakable lipids) may be acclimatized to amusement autoimmune diseases like Lupus. During the advance of these studies, he has developed adeptness in the abstraction of lipid and lipoprotein based mechanisms acclimation deepening and immunity, as able-bodied as the all-important anterior methods for accumulation spectrometry lipidomic analyses during a abiding collaborative accord with Dr. Steve Barnes. Added recently, Dr. Kabarowski has accustomed a adjustment for lipid imaging in cryosections by MALDI-Imaging Accumulation Spectrometry appliance exhaustion sublimation for cast application. This technology is actuality activated to a cardinal of areas, including anecdotic lipids with roles in modulating anarchic processes in acknowledgment to astute branch injury, autoimmunity and branch ache in Lupus, as able-bodied as those complex in the abasement of ocular action with ageing.

Website

Shuzhao Li, PhD

Assistant Professor, Accessory Director of Analytic Biomarkers Laboratory, Department of Medicine, Emory University

Dr. Li was accomplished in bioinformatics, and he has been accumulation computational developments with metabolomics and systems biology. His assignment in animal immunology activated all-embracing abstracts affiliation and arrangement clay to abut transcriptomic programs for antibiotic acknowledgment induced by several vaccines. These are aboriginal accomplish appear quantitative and systems clay of animal immunity, which is an basal allotment of best animal diseases. His mummichog software brought genome-scale metabolic models into the acreage of aerial throughput metabolomics, and enabled pathway/network assay for untargeted metabolomics. He strives to accompany these accurate developments to alone and attention medicine.

http://clinicalmetabolomics.org/

Peter Nemes, PhD

Peter Nemes is an Abettor Assistant of Allure (2013–present) at the George Washington University (GWU), beginning he acquired a PhD in allure in 2009 (advisor: Prof. Akos Vertes). He completed postdoctoral training in analytic neuroscience at the University of Illinois—Urbana-Champaign (mentor: Prof. Jonathan V. Sweedler). After confined as a Class Leader and Staff Adolescent at the US Food and Biologic Administration amid 2011–2013, Dr. Nemes abutting the adroitness of the GWU Department of Chemistry.

Research in the Nemes Class develops ultrasensitive and microanalytical platforms for high-resolution accumulation spectrometry to abstraction how metabolic and proteomic processes arrange accustomed corpuscle adverse during aboriginal development of the bearcat antecedent and the axial afraid system. Appliance these custom-built single-cell accumulation spectrometry systems, the Nemes Assay Accumulation has baldheaded ahead alien atomic differences amid distinct beginning beef that accord acceleration to adapted types of tissues during bearcat development. Furthermore, the accumulation has apparent baby molecules that are able to adapt the accustomed adorning fate of these beginning cells. These after-effects claiming our basal compassionate of atomic processes that are all-important for accustomed beginning development.

Prof. Nemes has authored 36 peer-reviewed publications, 6 book chapters, and 110 presentations. He is co-inventor of the patented and accountant LAESI accumulation spectrometry technology. In 2015, Prof. Nemes was called a Beckman Young Investigator by the Arnold and Mabel Beckman Foundation, and additionally accustomed the 2016 Arthur F. Findeis Award for Achievements by a Young Analytic Chemist by the Division of Analytic Allure of the American Actinic Society. In 2017, Prof. Nemes accustomed the DuPont Young Abettor Award and the Robert J. Cotter New Investigator Award by the US Animal Proteome Organization.

Wimal Pathmasiri, PhD

Wimal Pathmasiri, Ph.D. abutting the University of North Carolina at Chapel Hill Diet Assay Institute in March 2017 as a Assay Abettor Professor. Dr. Pathmasiri is absorbed in anecdotic biomarkers for the aboriginal apprehension of disease, and ecology comestible intervention. His efforts at UNC NRI will focus on compassionate the appulse of diet and artlessly occurring molecules in diet on gut microbiome accompanying metabolism.

Dr. Pathmasiri becoming his B.Sc. and M.Phil. from the University of Colombo, Sri Lanka, and a Licentiate of Philosophy from the Uppsala University, Sweden. He accustomed his Ph.D. in Allure from Uppsala University and conducted postdoctoral assay at the UNC Chapel Hill, and at RTI International.

Dr. Pathmasiri is an alive affiliate of the NIH Common Fund Eastern Regional Comprehensive Metabolomics Resource Amount (ERCMRC), area he has served as a assay biochemist for the accomplished 5 years. As a metabolomics scientist, he has contributed to assay in the areas of cancer, adolescence obesity, aboriginal activity acknowledgment to antibiotics, ecology exposure, branch disease, osteoarthritis, attenuate diseases, and toxicology.

Website

Andrew Patterson, PhD

Penn State University

I accept a ample accomplishments in atomic biology, biochemistry, and metabolism and am able-bodied abreast in appliance acid bend approaches including accumulation spectrometry-based metabolomics and gut microbial affiliation analysis. As a assay adolescent in the Class of Metabolism of the Civic Blight Institute, I was an basal and advantageous affiliate of the metabolomics affairs and activated my acquaintance to abstraction nuclear receptor dynamics, biologic metabolism, and diseases accompanying to metabolic affection and cancer. My efforts abundantly answer the development and identification of translational biomarkers appliance cutting-edge metabolomics platforms, including aqueous chromatography and gas chromatography accompanying with accumulation spectrometry and nuclear alluring resonance spectroscopy. I accept cogent and connected almanac of important and atypical allegation (Google Academic h-index = 29) in the acreage of metabolomics and biomedicine in the anatomy of affidavit appear in abundant journals including Analytic Chemistry, Corpuscle Metabolism, Ecology Bloom Perspectives, Ecology Science and Technology, Hepatology, Journal of Biological Chemistry, Journal of Analytic Investigation, Journal of Proteome Research, Nature Communications, and Radiation Research; arrive assay articles, in such publications as in Nature Reviews Cancer, Accumulation Spectrometry Reviews and Actinic Assay in Toxicology; a book affiliate appear in General and Activated Toxicology; and seminars and lectures presented at abundant local, national, and all-embracing meetings, including Metabomeeting in the UK (2014, 2015), Microsomes and Biologic Oxidations in China (2010) and Germany (2014), and Society of Toxicology (2015).

Website

Jeevan Prasain, PhD

Dr. Prasain is an Abettor Assistant of Pharmacology and Toxicology at UAB. He accustomed his undergraduate and master’s training (Chemistry) at Tribhuvan University, Nepal and his Ph.D. at Toyama Medical & Pharmaceutical University, Japan. His adeptness is in the use of NMR and LC-MS for the assay and identification of accustomed products. He will be demonstrating the use of LC-MS methods for the assay of metabolite classes.

Website

Delisha Stewart, PhD

Dr. Delisha Stewart accustomed her Ph.D. in Biochemistry from the University of Alabama at Birmingham (UAB). Following postdoctoral fellowships at the University of Delaware, UAB and UNC-Chapel Hill, she completed her training with the NIH Eastern Regional Comprehensive Metabolomics Resource Amount (ERCMRC) at RTI All-embracing to apprentice metabolomics. She uses genomics, metabolomics and high-throughput atomic bioassays to abstraction metabolic dysfunction in blight and immunological diseases, best absorbed in the coaction amid the allowed arrangement and malignancy. In March 2017, she abutting the Department of Diet at UNC-Chapel Hill as a Assay Abettor Professor, relocating with the ERCMRC to the Diet Assay Institute. She continues to advance all blight and immunology-focused studies, with an added focus on the access of diet on blight bloom disparities. Her assay aims to bigger characterize etiological and accelerating microenvironments of breast and added types of hormonally-associated cancers, analyze diagnostically and therapeutically accordant biomarkers and actuate the role of adapted comestible states on disparate assay outcomes.

Website

Hemant Tiwari, PhD

Dr. Tiwari is the Co-Director of the Metabolomics Workshop. He accustomed his Ph.D. in mathematics from the University of Notre Dame, South Bend, Indiana. While actuality a adroitness at the University of Maine, he got absorbed in statistical genetics, and completed a post-doctoral acquaintance in Statistical Assay beneath Prof. Robert Elston in the Department of Biometry and Assay at Louisiana State University Medical Center, New Orleans and at the Case Western Reserve University in Cleveland. Subsequently, he formed as a adroitness affiliate in the Department of Epidemiology and Biostatistics at Case Western Reserve University. In January 2002, he abutting UAB as a adroitness in the Department of Biostatistics (Section on Statistical Genetics). His assay interests accommodate Genetic Linkage Analysis, Disequilibrium Mapping, Population Genetics, Atomic Evolution, Bioinformatics, and Assay of Infectious Diseases. Currently, he is complex in gene mapping studies of epilepsy, SLE, phonological disorders, and dental traits. He is the Head of the Section on Statistical Genetics, the William “Student” Sealy Gosset Professor, Director of the Biostatistics Pre-Doctoral NHLBI Training Affairs and Director of the Post-Doctoral NHLBI Training Affairs in Statistical Genetics. He additionally is the Director of the NIGMS-funded Civic Abbreviate Advance in Statistical Assay and Genomics.

Website: http://www.soph.uab.edu/ssg/people/tiwari

Karan Uppal, PhD

My assay focuses on computational metabolomics, commutual -omics, and development of apparatus acquirements techniques for allegory and extracting ability and advice from “BIG” omics data, analytic text, and biomedical literature. I accept a academic training in Bioinformatics with a focus on the development and appliance of statistical and apparatus acquirements techniques for allegory high-throughput -omics abstracts and biomedical/clinical text. I accept acquaintance in allegory and developing computational pipelines for metabolomics, epigenomics, proteomics, and transcriptomics data. I additionally accept acquaintance in developing accoutrement (https://sourceforge.net/u/kuppal2/profile/) and algorithms for arrangement based comment of high-resolution accumulation spectrometry data, admiration protein-protein interactions, and commutual assay of –omics data. I developed xMSanalyzer that optimizes the achievement of absolute LC/MS abstracts processing software such as apLCMS and XCMS for bigger affection detection. The software allows apprehension of quantitatively reliable low affluence and capricious chemicals and chemicals that are present in alone baby subset of samples. I accept developed MetabNet for metabolome-wide affiliation studies and algorithms for computational anticipation of metabolite identity. I accept additionally developed R bales for supervised and unsupervised assay of metabolomics abstracts and for anecdotic metabolic biomarkers appliance univariate and multivariate affection alternative techniques such as PLSDA. I additionally accept the adeptness to accommodate amalgamate abstracts (metabolomics and gene expression; metabolomics and proteomics) and analyze the arrangement assay or modules of co-regulating metabolites, which would abetment in anecdotic the affiliation of the alien chemicals with account to diseases, analytic traits, and biological pathways. I accept acquaintance in developing abstract mining accoutrement and algorithms for automatic summarization and ability assay from analytic and biomedical text. I am accomplished in R, Java, Perl, Python, C , Flex, PHP, ActionScript, JavaScript, MySQL, and database and web-application development.

Hui Wu, PhD

Dr. Wu is a Abettor in the Departments of Pediatric Dentistry and Microbiology. Dr. Wu accustomed his Ph.D. amount in Corpuscle and Atomic Assay in 1999 at the University of Vermont. After he completed his postdoctoral training there, Dr. Wu abutting the UAB adroitness as an Abettor Assistant in 2004. Dr. Wu was answer to abounding Abettor in 2012. He was a almsman of NIH/NIHDCR Academic and Adroitness Transition Award in 2004. In 2011 he accustomed IADR/GSK Innovation in Oral Care Award and was afresh called as a almsman for 2014 UAB Graduate Dean’s Award for Excellence in Mentoring.

Website

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