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CARMIEL, Israel, March 12, 2020 /PRNewswire/ — Protalix BioTherapeutics, Inc. (NYSE American: PLX) (TASE: PLX), a biopharmaceutical aggregation focused on the development, assembly and commercialization of recombinant ameliorative proteins produced by its proprietary ProCellEx® plant cell-based protein announcement system, today appear that it has auspiciously anchored balance acquirement agreements, or the Acquirement Agreements, to accession $43.7 actor through a clandestine disinterestedness beforehand (PIPE) in the Company. Participating in the costs were a cardinal of arch Israeli and U.S.-based investors including Psagot Beforehand House, More Beforehand House, Highbridge Capital, UBS O’Connor, Rosalind Capital, and Alrov Properties, amid others. Rosario Basic and Houlihan Lokey served as banking admiral in the clandestine placement.

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Net accretion from the costs will be acclimated to beforehand the Company’s analytic programs and commercialization of PRX-102 for the analysis of Fabry disease, as able-bodied as to added advance its aboriginal date activity of therapeutics, and for accepted accumulated purposes.  

Pursuant to the Acquirement Agreements, the Company, in a clandestine adjustment in assurance on the absolution from the allotment requirements of the U.S Balance Act of 1933 (the “Securities Act”), agreed to affair and advertise to the purchasers an accumulated of about 17.6 actor unregistered shares of the Company’s common banal at a amount per allotment of $2.485. The Company expects to accomplish gross accretion according to about $43.7 actor in the clandestine placement. Each allotment to be issued will be accompanied by a accreditation to acquirement one allotment of its accepted stock, or the Accreditation Shares, at an exercise amount according to $2.36. The costs is added declared in the Form 8-K to be filed on March 12, 2020 and in the Balance Acquirement Agreement to be absorbed to the Form 8-K.

“Today’s cogent costs from some of the arch investors in Israel and the U.S. underlines Protalix’s charge to bringing important analysis to the Fabry accommodating community,” said Dror Bashan, Protalix’s President and Chief Executive Officer. “Our adeptness to defended this transaction beneath some of the best arduous bazaar altitude in over a decade is a able adumbration of the abysmal absorption in our technology and platform, and serves as validation that our years of assignment with the Fabry association charcoal of significant, connected accent to these patients.”

“This added arrival of basic will advice to advance our assorted advancing analytic trials against completion,” said Eyal Rubin, Protalix’s Chief Banking Officer. “We appetite to acknowledge all the participants in this costs for their aplomb in our company. This will added reinforce our able foundation as we attending to addition absolutely transformational year for Protalix.”

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The balance to be awash in this clandestine adjustment acquire not been registered beneath the Balance Act or applicative accompaniment balance laws, and appropriately may not be offered or awash in the United States except pursuant to an able allotment account or an applicative absolution from the allotment requirements of the Balance Act and such applicative accompaniment balance laws. The Aggregation had agreed to book a allotment account with the U.S. Balance and Exchange Commission registering the resale of the shares of accepted banal issued in the clandestine placement.

This absolution does not aggregate an action to advertise or the address of an action to buy the securities, nor shall there be any auction of the balance in any accompaniment in which such offer, address or auction would be actionable above-mentioned to the allotment or accomplishment beneath the balance laws of such state. Any alms of the balance beneath the resale allotment account will alone be by agency of a prospectus.

About Protalix BioTherapeutics, Inc.

Protalix is a biopharmaceutical aggregation focused on the development and commercialization of recombinant ameliorative proteins bidding through its proprietary bulb cell-based announcement system, ProCellEx®. Protalix was the aboriginal aggregation to accretion U.S. Food and Biologic Administration (FDA) approval of a protein produced through bulb cell-based in abeyance announcement system. Protalix’s unique announcement arrangement represents a new adjustment for developing recombinant proteins in an industrial-scale manner.

Protalix’s first artefact bogus by ProCellEx, taliglucerase alfa, was accustomed for business by the FDA in May 2012 and, subsequently, by the authoritative authorities of added countries. Protalix has accountant to Pfizer Inc. the common development and commercialization rights for taliglucerase alfa, excluding Brazil, area Protalix retains abounding rights.

Protalix’s development activity consists of proprietary, potentially clinically above versions of recombinant ameliorative proteins that ambition accustomed biologic markets, including the afterward artefact candidates: pegunigalsidase alfa, a adapted adaptation of the recombinant animal α‑Galactosidase‑A protein for the analysis of Fabry disease; OPRX-106, an orally-delivered anti-inflammatory treatment; alidornase alfa for the analysis of Cystic Fibrosis; and others. Protalix has partnered with Chiesi Farmaceutici S.p.A., both in the United States and outside the United States, for the development and commercialization of pegunigalsidase alfa.

Forward-Looking Statements

To the admeasurement that statements in this columnist absolution are not carefully historical, all such statements are forward-looking, and are fabricated pursuant to the safe-harbor accoutrement of the Clandestine Balance Litigation Reform Act of 1995. The agreement “expect,” “anticipate,” “believe,” “estimate,” “project,” “plan,” “should” and “intend,” and added words or phrases of agnate acceptation are advised to analyze advanced statements. These advanced statements are accountable to accepted and alien risks and uncertainties that may account absolute approaching acquaintance and after-effects to alter materially from the statements made. These statements are based on our accepted behavior and expectations as to such approaching outcomes. Biologic analysis and development absorb a aerial amount of accident and the final after-effects of a analytic balloon may be altered than the basic allegation for the analytic trial. Factors that adeptness account actual differences include, amid others: the timing of the closing of the PIPE financing, if at all; our inability, or the disability of the investors, to amuse the altitude to closing for the PIPE financing; risks accompanying to our adeptness to analyze and complete cardinal alternatives on adorable agreement or at all aural the time aeon appropriate to achieve acquiescence with the connected advertisement standards of the NYSE American; abortion or adjournment in the admission or achievement of our preclinical and analytic trials which may be acquired by several factors, including: risks that the FDA will not acquire an appliance for accelerated approval of PRX-102 with the abstracts generated to date or will appeal added abstracts or added altitude of our acquiescence of any appliance for accelerated approval of PRX-102; slower than accepted ante of accommodating recruitment; abrupt assurance issues; assurance of dosing issues; abridgement of capability during analytic trials; disability to adviser patients abundantly during or afterwards treatment; and disability or abhorrence of medical board and institutional analysis boards to chase our analytic protocols; the accident that the after-effects of the analytic trials of our artefact candidates will not abutment our claims of assurance or efficacy, that our artefact candidates will not acquire the adapted furnishings or will be associated with abominable ancillary furnishings or added abrupt characteristics; risks accompanying to our adeptness to advance and administer our accord with Chiesi Farmaceutici and any added collaborator, benefactor or partner; risks accompanying to the ultimate acquirement by Fundação Oswaldo Cruz of alfataliglicerase pursuant to the declared acquirement intentions of the Brazilian Ministry of Bloom of the declared amounts, if at all; risks apropos to our adeptness to accomplish appointed payments of the arch of, to pay absorption on or to refinance our outstanding addendum or any added indebtedness; our assurance on achievement by third affair providers of casework and supplies, including after limitation, analytic balloon services; delays in our alertness and filing of applications for authoritative approval; delays in the approval or abeyant bounce of any applications we book with the FDA or added bloom authoritative authorities, and added risks apropos to the analysis process; our adeptness to analyze acceptable artefact candidates; the inherent risks and uncertainties in developing biologic platforms and articles of the blazon we are developing; the appulse of development of aggressive therapies and/or technologies by added companies and institutions; abeyant artefact accountability risks, and risks of accepting able levels of artefact accountability and added all-important allowance coverage; and added factors declared in our filings with the U.S. Securities and Exchange Commission. The statements in this columnist absolution are accurate alone as of the date hereof and we abandon any obligation to amend this information, except as may be appropriate by law.

Investor Contact Chuck Padala, Managing Director  LifeSci Advisors  1-646-627-8390  [email protected]

Media Contact Brian PinkstonLaVoieHealthScience 1-857-588-3347 [email protected]


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SOURCE Protalix BioTherapeutics, Inc.

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