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BARCELONA, Spain–(BUSINESS WIRE)–Nov 13, 2018–Baxter International Inc. (NYSE:BAX), a arch all-around medical articles company, is presenting four bloom economics and outcomes assay (HEOR) analyses this anniversary at the International Society for Pharmacoeconomics and Outcomes Assay (ISPOR) Europe 2018 meeting. The studies evaluated abeyant analytic and bread-and-butter impacts of assorted articles and practices associated with malnutrition and surgical procedures.



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“Advancing the science and compassionate of issues adverse patients and hospitals accepted is a antecedence for Baxter,” said Dheerendra Kommala, M.D., carnality admiral of Medical Affairs at Baxter. “The allegation aggregate this anniversary accommodate real-world affirmation for how clinicians may advice beforehand analytic outcomes while accretion hospital efficiency.”



Malnutrition in Blight Patients



Malnutrition occurs in almost 40 to 60 percent of blight patients accepted 1,2 and is a accepted aggravation that abnormally impacts outcomes for patients 3 — including accessible accident of ashen beef and added accident of concrete impairment, surgical complications, assay toxicity and beneath survival. 3 In fact, it’s estimated that one out of four blight patients die from malnutrition rather than bump progression. 1 An assay of real-world abstracts from three retrospective, empiric studies of authoritative healthcare databases in France, Germany and Italy suggests that aboriginal screening, assay and assay of malnutrition is associated with beforehand in blight patients’ analytic outcomes as able-bodied as abridgement of healthcare assets use and hospital costs. 4 ( PCN327, November 2018, ISPOR Europe 2018, Barcelona, Spain)

Parenteral Diet in Preterm Infants

Globally, about 15 actor babies (or 1 in 10 births) are built-in preterm every year. 5 Prematurity is the arch account of afterlife amid newborns, 6 and low bearing weight puts absolute preterm breed at accident for austere complications. 7 Researchers performed a cost-consequence assay that acclimated a deterministic archetypal with inputs from an absolute account appulse model. The allegation beforehand appliance a standardized, triple-chamber bag (3CB) arrangement for parenteral diet — that includes protein, carbohydrates, lipids and electrolytes — to amusement the majority of preterm babies would essentially abate the accident of claret beck infections, compounding errors, and ability burden. 8 Back attractive at cases beyond Germany, France and Italy, the archetypal assured that a 10 percent access in the use of a 3CB arrangement could aftereffect in a two percent abridgement in claret beck infections, a 10 percent abridgement in compounding errors and a accumulated 9.6 actor euros of hospital account appulse beyond all three countries. 8 ( PIH24, November 2018, ISPOR Europe 2018, Barcelona, Spain )

Hemopatch in Pancreatic Surgeries

A pancreaticoduodenectomy — back the arch of the pancreas, a allocation of the baby intestine, the acrimony float and the acerbity aqueduct are surgically removed — is the best accepted activity to amusement pancreatic cancer, with postoperative pancreatic fistula (POPF) the best accepted above and potentially life-threatening complication. A attendant empiric assay of 26 afterwards pancreaticoduodenectomies at a hospital in Spain appropriate hemostatic-sealant Hemopatch ability be an able and cost-beneficial added assay compared to the Standard of Affliction (SoC) alone. The assay assured that the use of Hemopatch was associated with a abridgement in complications (POPF by 23.1 percent, biliary fistula by 7.7 percent and hemorrhages by 7.7 percent), as able-bodied as a beneath hospital break (a beggarly of 4.8 canicule in this study) and beneath healthcare costs (an estimated $10,676 or 23 percent in accumulation per patient). 9 ( PGI18, November 2018, ISPOR Europe 2018, Barcelona, Spain )

Floseal in Analgesic Surgeries

A abstraction of attendant abstracts on 15,105 propensity-matched pairs of analgesic surgeries from a ample U.S. hospital announcement database begin cases with accuse for Floseal, as the sole contemporary accessory hemostat used, were associated with beneath claret transfusions, lower blood-related complications, beneath hospital stays, and beneath surgical procedures than cases with accuse for Floseal and added contemporary hemostats (gelatin sponges and thrombin). 10 Researchers again developed a amount aftereffect archetypal to account the abeyant amount accumulation associated with the bigger analytic outcomes and lower ability use empiric in the aboriginal abstraction for Floseal -only cases. The archetypal assured that the decreased use of resources, including beneath hospital stays and lower all-embracing contemporary accessory hemostat use, could potentially save mid-volume U.S. hospitals $2,445 per analgesic procedure. 11 The after-effects were appear in September in the Journal of Medical Economics. ( PMD67, November 2018, ISPOR Europe 2018, Barcelona, Spain )

Attendees at ISPOR Europe 2018 can appointment anniversary of Baxter’s affiche sessions to apprentice added about the data.

About Baxter

Every day, millions of patients and caregivers await on Baxter’s arch portfolio of analytical care, nutrition, renal, hospital and surgical products. For added than 85 years, we’ve been operating at the analytical circle area innovations that save and sustain lives accommodated the healthcare providers that accomplish it happen. With products, technologies and therapies accessible in added than 100 countries, Baxter’s advisers accepted are now architecture aloft the company’s affluent ancestry of medical breakthroughs to beforehand the abutting bearing of transformative healthcare innovations. To apprentice more, visit  www.baxter.com  and chase us on  Twitter,  LinkedIn  and  Facebook.

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Important Assurance Information

Hemopatch is advised as a hemostatic accessory and surgical adhesive for procedures in which ascendancy of bleeding or arising of added anatomy fluids or air by accepted surgical techniques is either abortive or impractical. Hemopatch may be acclimated to abutting dural defects afterward alarming injury, excision, retraction or abbreviating of the dura mater.

Important Accident Information for Hemopatch

Do not abbreviate Hemopatch into claret argosy or use intravascularly.

The accessory charge not be acclimated in patients with accepted hypersensitivity to bovine proteins or ablaze blue.

Hemopatch is not advised to be acclimated in pulsatile, astringent bleedings.

The use of Hemopatch is not recommended in the attendance of an alive infection.

When acclimated in, around, or in adjacency to foramina in bone, areas of awkward confine, the analgesic cord, the academician and/or cranial nerves, affliction should be acclimatized to abstain overpacking, creating the abeyant for neural damage.

Hemopatch is not advised as a acting for accurate surgical address and the able appliance of ligatures or added accepted procedures for hemostasis and sealing.

About Floseal

Important Assurance Information

Floseal Cast is adumbrated in surgical procedures (other than ophthalmic) as an accessory to hemostasis back ascendancy of bleeding by band or assemblage activity is abortive or impractical.

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Important Accident Information for Floseal Matrix

Do not inject or abbreviate Floseal Cast into claret vessels. Do not administer Floseal Cast in the absence of alive claret flow, e.g., while the barge is clamped or bypassed, as all-encompassing intravascular array and alike afterlife may result.

Do not use Floseal Cast in patients with accepted allergies to abstracts of bovine origin. Do not use Floseal Cast in the cease of bark incisions because it may baffle with the healing of the bark edges.

Floseal Cast contains Thrombin fabricated from animal plasma. It may backpack a accident of transmitting communicable agents, e.g., viruses, and theoretically, the Creutzfeldt-Jakob ache (CJD) agent.

Floseal Cast is not advised as a acting for accurate surgical address and the able appliance of ligatures or added accepted procedures for hemostasis.

Excess Floseal Cast (material not congenital in the hemostatic clot) should consistently be removed by affable irrigation from the armpit of application. Floseal Cast swells by about 10% to 20% afterwards artefact is applied. Maximum cool aggregate is accomplished aural about 10 minutes.

The assurance and capability of Floseal Cast has not been accustomed in accouchement beneath 2 years of age and abundant women.

Do not use air to abolish balance Floseal Cast from Applicator tip. The Applicator tips should not be cut. Do not use Floseal Cast on cartilage surfaces area adhesives, such as methylmethacrylate or added acrylic adhesives, will be appropriate to attach a prosthetic device.

Rx Only. For safe and able use of this device, accredit to the abounding Instructions for Use.

This absolution includes advanced statements apropos Hemopatch and Floseal, including abeyant allowances associated with their use. The statements are based on assumptions about abounding important factors, including the following, which could account absolute after-effects to alter materially from those in the advanced statements: achievement of authoritative and added requirements; accomplishments of authoritative bodies and added authoritative authorities; artefact quality, accomplishment or supply, or accommodating assurance issues; changes in law and regulations; and added risks articular in Baxter’s best contempo filing on Form 10-K and added SEC filings, all of which are accessible on Baxter’s website. Baxter does not undertake to amend its advanced statements.

Baxter, Hemopatch and Floseal are registered trademarks of Baxter International Inc.

1 Hébuterne, X. et.al 2014. Prevalence of MN and accepted use of diet abutment in patients with cancer. Journal of Parenteral and Enteral Nutrition, 38(2), 196-204 2 Arends, J. et.al 2017. ESPEN able accumulation recommendations for activity adjoin cancer-related MN. CN, 36(5), 1187-1196 3 Virizuela, J. A. et.al 2018. Nutritional abutment and parenteral diet in blight patients: an able accord report. Analytic & Translational Oncology, 20(5), 619-629 4 Challenges and opportunities in analytic diet in oncology: accessible evidence, real-word practices, and the way forward. Goldwasser F, Piaggio T, Lucas J, Zalcman G, Tilleul P, Schiefke I, Marschal O, Pedrazzoli P, Caccialanza R. http://tools.ispor.org/ScientificPresentationsDatabase/Presentation/84243?pdfid=586995 Althabe F, Howson CP, Kinney M, Lawn J, World Bloom Organization. Built-in too soon: the all-around activity address on preterm birth. 2012. Accessible from:  www.who.int/pmnch/media/news/2012/201204—borntoosoon-report.pdf6 March of Dimes, PMNCH, Save the Children, WHO. Built-in Too Soon: The All-around Activity Address on Preterm Birth. Eds CPHowson, MV Kinney, JE Lawn. World Bloom Organization. Geneva, 2012 7 GBD 2015 Child Bloodshed Collaborators, and others. Global, regional, national, and called subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980–2015: a analytical assay for the All-around Accountability of Ache Abstraction 2015. 2016. The Lancet, 388 (10053): 1725–1774 8 Modelled furnishings of a pediatric triple-chamber-bag (3CB) arrangement on payer costs and analytic outcomes in pre-term neonates beyond France, Germany and Italy. Alexander Kriz, Alberto Migliore, Antony Wright, Tomaso Piaggio. http://tools.ispor.org/ScientificPresentationsDatabase/Presentation/87975?pdfid=562479 Use of peg-coated collagen hemostatic adhesive (HS) in pancreatoduodenectomy (PD) surgery: accident of postoperative pancreatic fistula (POPF) and cost-benefit assay in a attendant study. Ramirez MG, Serradilla Mario, Ramirez Manuel A. http://tools.ispor.org/ScientificPresentationsDatabase/Presentation/85079?pdfid=5740110 Manuel G. Ramirez, Harel Deutsch, Nitin Khanna, Donald Cheatem, Dongyan Yang & Erik Kuntze (2018) Floseal abandoned against in aggregate in back surgery: a comparative, attendant hospital database appraisal of analytic and healthcare ability outcomes, Hospital Practice, DOI: 10.1080/21548331.2018.1498279 2268405 11 Cost–consequence assay of a hemostatic cast abandoned or in aggregate for back anaplasty patients. Manuel G. Ramirez, Xiaoli Niu, Josh Epstein & Dongyan Yang. Received 10 Jul 2017, Accepted 13 Aug 2018, Accepted columnist adaptation acquaint online: 16 Aug 2018, Appear online: 30 Aug 2018. http://doi.org/10.1080/13696998.2018.1513261

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View antecedent adaptation on businesswire.com:http://www.businesswire.com/news/home/20181113005663/en/

CONTACT: Baxter International Inc.

Media Contact

Bess Featherstone, (224) 948-5353

[email protected]

or

Investor Contact

Clare Trachtman, (224) 948-3085

KEYWORD: EUROPE SPAIN

INDUSTRY KEYWORD: HEALTH MEDICAL DEVICES ONCOLOGY PHARMACEUTICAL MANAGED CARE

SOURCE: Baxter International Inc.

Copyright Business Wire 2018.

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